Liposomal Vitamin B15 DMG Dimethylglycine

Dimethylglycine, also known as DMG, is a powerful methyl donor with a uniquely fascinating history. Dimethylglycine was a part of the original vitamin B15 structure known as pangamic acid. Research over the years gave evidence that the biological activity ascribed to pangamate B15, was in fact, due to DMG.

DMG is an active amino acid and intermediate metabolite in the one-carbon Choline cycle. Its primary function is to contribute methyl groups for the methylation reactions and provide other essential building blocks. Scientists have been aware of DMG’s potential benefits for over a half-century, and it’s been used to enhance athletic performance for decades.* Its promise was first put to use as an addition to equine diets for racehorses in the 1970s and 1980s. Even though it has been used for decades, this phenomenal food substance’s benefits have only recently reached mainstream awareness in the general public.

The human body can synthesize significant amounts of dimethylglycine by metabolizing choline or losing one trimethylglycine methyl group through the homocysteine pathway. However, DMG is broken down so quickly and used in so many different pathways that its levels are spread thin and never get a chance to build up. As such, the most effective way of increasing quantities of dimethylglycine in the human body is through supplementation.

Because DMG is such a potent metabolic enhancer, it supports a plethora of systems in the human body.* It’s similar to the amino acid, glycine,
but with two methyl groups attached. When DMG gives up these methyl groups to the one-carbon pathway’s methyl pool, they become part of the molecular building blocks that produce everything from neurotransmitters and hormones to nucleic acids and mitochondrial function.* Much of the scientific focus around DMG has been geared towards improved cellular energy levels, immune function, and advanced glutathione production.*

Because of DMG’s methyl donating properties, it helps recycle SAMe and Glutathione, the latter of which is a critical aspect of the human body’s detoxification process of both endogenous and xenobiotic compounds.* Glutathione is also one of the most impactful free-radical scavengers that humans, plants, and animals produce.*

Although a handful of foods contain glutathione, historically, it has low bioavailability. Our bodies need the raw materials for the glutathione synthesis process, and DMG is an efficient fuel by supplying both a methyl group and glycine for its production. Supporting glutathione production through the enhanced methylation and building-blocks provided by DMG is critical to liver health and supporting natural detoxification and the scavenging of free-radicals.*

DMG has proven to be a comprehensive cellular metabolite that can boost various physiological functions to support optimal wellbeing and overall health.* DMG raises the efficiency and productivity of the methylation metabolic pathway, showing us that this upstream cellular support may be beneficial in supporting as well as minimizing several bodily functions.*

Key Benefits of DMG

• DNA replication and repair*

• Immune response as a metabolic enhancer*

• Supports cardiovascular health*

• Supports liver health & detox*

• Supports brain health and cognition*

• Supports respiratory function through improved circulation and oxygen utilization*

• Stress support*

• Free-radical support through glutathione recycling*

• Supports healthy aging*

• Improves athletic performance*